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Murray is listed as the favorite among the two former Heisman winners at 33/1 this season, according to the sportsbook. By comparison, Caesars opened Murray's rookie campaign with 75-1 odds last season.
Cleveland quarterback Baker Mayfield is listed at 40/1 odds – drastically down from the 9/1 oddsmakers opened him last season.
Kansas City quarterback Patrick Mahomes is the favorite at 4/1 after winning Super Bowl LIV.
Patrick Mahomes 4/1
Russell Wilson 5/1
Lamar Jackson 6/1
Deshaun Watson 12/1
Aaron Rodgers 16/1
Drew Brees 16/1
Kyler Murray 33/1
Tom Brady 33/1
Baker Mayfield 40/1